Heart Failure Monitoring System Based on Wearable and Information Technologies

In Europe, Cardiovascular Diseases (CVD) are the leading source of death, causing 45% of all deceases. Besides, Heart Failure, the paradigm of CVD, mainly affects people older than 65. In the current aging society, the European MyHeart Project was created, whose mission is to empower citizens to fight CVD by leading a preventive lifestyle and being able to be diagnosed at an early stage. This paper presents the development of a Heart Failure Management System, based on daily monitoring of Vital Body Signals, with wearable and mobile technologies, for the continuous assessment of this chronic disease. The System makes use of the latest technologies for monitoring heart condition, both with wearable garments (e.g. for measuring ECG and Respiration); and portable devices (such as Weight Scale and Blood Pressure Cuff) both with Bluetooth capabilitie

HeartCycle: User interaction and patient education

Cardiovascular Diseases are the most prevalent and serious chronic conditions existing nowadays. They are the primary cause of death in the world and generate enormous expenditures to the health systems. Tele-monitoring and personal health systems have proven to be good options for tackling this situation; however they are still lacking many functionalities. It is necessary to find solutions that allow health professionals to follow up patients more closely and efficiently, while reducing the non-adherence of patients to the treatment regime. HeartCycle research project (partially funded by the European Commission) has developed a personal health system for cardiovascular diseases management with the aim to address this problem. This paper describes the Patient Loop of this solution, including the different components, the adopted user interaction, and the implemented patients education and coaching strategy

Hybrid Energy Storage and Hydrogen Supply Based on Aluminum—a Multiservice Case for Electric Mobility and Energy Storage Services

The realization of a fully decarbonized mobility and energy system requires the availability of carbon-free electricity and fuels which can be ensured only by cost-efficient and sustainable energy storage technologies. In line with this demand, a techno-economic evaluation of aluminum as a cross-sectoral renewable energy carrier is conducted. The assessment, based on a newly developed process, involves the wet combustion of Aluminum at 700 degrees C resulting in heat and hydrogen (H-2) generation. The designed conversion plant enables the contemporaneous generation of electricity and on demand H-2 (up to 4 MW and 46.8 kg h(-1)) with round-trip efficiencies as high as 40.7% and full recycling of the Al2O3 waste. This study, assuming the carbon-free production of Al and three different energy cost scenarios, proves the feasibility of the e-fueling station business case. The overall energy conversion including fuel production (power-to-Al), utilization (Al-to-power and Al-to-H-2), and recycling requires a capital investment of 5200 euro per kW installed power without additional primary material demand. Hence, the estimated power-to-X cost for the Al-based H-2 is estimated in the range of 4.2-9.6 euro kg(-1) H-2, while wind and solar power based green H-2 production cost varies from 6.5 to 12.1 euro kg(-1) H-2

Public Health Observatories: a learning community model to foster knowledge transfer for sustainable cities

[EN] A Public Health Observatory (PHO) is a platform to provide “health intelligence” as a service for a specific population. The World Health Organization (WHO) identifies the primary purposes of PHOs as “monitoring health situations and trends, including assessing progress toward agreed-upon health-related targets; producing and sharing evidence; and, supporting the use of such evidence for policy and decision making” For the purposes of the PULSE project, create an observatory to function as a unique point of access to the PULSE technology for people both inside and outside the project consortium.Specifically, we create a platform for e-learning and knowledge sharing that it can be easily navigated by lay persons that are interested in learning about or participating in the PULSE project. We targeted specifically policymakers, clinicians, as well as leaders and citizens in other cities. As a concept, it reflects the principles participation, sustainability, and collaboration across sectors and levels of government The Observatory leverages on the Health in All Policies (HiAP) framework. HiAP is a cross-sectoral approach to public policy that systematically takes into account the health implications of decisions, seeks synergies, and avoids harmful health impacts in order to improve population health and health equity.PULSE project has been founded by the European Union’s Horizon 2020 research and innovation programme, and it is documented in the grant agreement No 727816. Specifically. PULSE has been founded under the call H2020-EU-3.1.5. in the topic SCIPM-18-2016-Big Data supporting Public Health policies. More information on http://www.project-pulse.euVito, D.; Ottaviano, M.; Cabrera, MF.; Teriús Padrón, JG.; Casella, V.; Bellazzi, R. (2020). Public Health Observatories: a learning community model to foster knowledge transfer for sustainable cities. En 6th International Conference on Higher Education Advances (HEAd'20). Editorial Universitat Politècnica de València. (30-05-2020):1383-1390. https://doi.org/10.4995/HEAd20.2020.11285OCS1383139030-05-202

A platform for the development of patient applications in the domain of personalized health

Personalized health (p-health) systems can contribute significantly to the sustainability of healthcare systems, though their feasibility is yet to be proven. One of the problems related to their development is the lack of well-established development tools for this domain. As the p-health paradigm is focused on patient self-management, big challenges arise around the design and implementation of patient systems. This paper presents a reference platform created for the development of these applications, and shows the advantages of its adoption in a complex project dealing with cardio-vascular diseases

Well-being Forecasting using a Parametric Transfer-Learning method based on the Fisher Divergence and Hamiltonian Monte Carlo

INTRODUCTION: Traditional personalised modelling typically requires sufficient personal data for training. This is a challenge in healthcare contexts, e.g. when using smartphones to predict well-being. OBJECTIVE: A method to produce incremental patient-specific models and forecasts even in the early stages of data collection when the data are sporadic and limited. METHODS: We propose a parametric transfer-learning method based on the Fisher divergence, where information from other patients is injected as a prior term into a Hamiltonian Monte Carlo framework. We test our method on the NEVERMIND dataset of self-reported well-being scores. RESULTS: Out of 54 scenarios representing varying training/forecasting lengths and competing methods, our method achieved overall best performance in 50 (92.6%) and demonstrated a significant median difference in45 (83.3%). CONCLUSION: The method performs favourably overall, particularly when long-term forecasts are required given short-term data

Analyzing Creativity in the Light of Social Practice Theory

In this work, starting from the social practice theory, we identified two kinds of creativity: a situational creativity that takes place when, starting from a defined situation, a social practice is played; and a creativity of habit that concerns the agents' capacity for generating new practices from habit when the situation is not defined or is unexpected. To test this hypothesis, the Torrance Test of Creative Thinking (Verbal Form A) was analyzed in the light of praxeology, and the results are analyzed in a computational creativity perspective

The role of disposition to critical thinking in digital game-based learning

The relationship between the development of 21st-century skills and game-based learning is a field to explore. Among the 21-st century skills, critical thinking is one of the most analyzed skills. This study aims to deepen the relationship between learning and disposition to critical thinking (DCT) in the context of Serious Games (SGs). In particular, starting from the evidence of previous work, that highlighted a positive effect of the DCT on game performance, this study analyzes how the DCT also affects the explicit learning gained by the players. This work highlights that the DCT has a crucial role in explicit knowledge acquisition and how the improvement of game performance is a direct consequence of DCT through a path analysis methodology

Vitamin D treatment prevents uremia-induced reductions in aortic microRNA-145 attenuating osteogenic differentiation despite hyperphosphatemia

In chronic kidney disease, systemic inflammation and high serum phosphate (P) promote the de-differentiation of vascular smooth muscle cells (VSMC) to osteoblast-like cells, increasing the propensity for medial calcification and cardiovascular mortality. Vascular microRNA-145 (miR-145) content is essential to maintain VSMC contractile phenotype. Because vitamin D induces aortic miR-145, uremia and high serum P reduce it and miR-145 directly targets osteogenic osterix in osteoblasts, this study evaluated a potential causal link between vascular miR-145 reductions and osterix-driven osteogenic differentiation and its counter-regulation by vitamin D. Studies in aortic rings from normal rats and in the rat aortic VSMC line A7r5 exposed to calcifying conditions corroborated that miR-145 reductions were associated with decreases in contractile markers and increases in osteogenic differentiation and calcium (Ca) deposition. Furthermore, miR-145 silencing enhanced Ca deposition in A7r5 cells exposed to calcifying conditions, while miR-145 overexpression attenuated it, partly through increasing α-actin levels and reducing osterix-driven osteogenic differentiation. In mice, 14 weeks after the induction of renal mass reduction, both aortic miR-145 and α-actin mRNA decreased by 80% without significant elevations in osterix or Ca deposition. Vitamin D treatment from week 8 to 14 fully prevented the reductions in aortic miR-145 and attenuated by 50% the decreases in α-actin, despite uremia-induced hyperphosphatemia. In conclusion, vitamin D was able to prevent the reductions in aortic miR-145 and α-actin content induced by uremia, reducing the alterations in vascular contractility and osteogenic differentiation despite hyperphosphatemia